What Are The Common Causes of Neuropathy?

Idiopathic peripheral neuropathy – when there is no specific cause found for peripheral neuropathy.

Diabetes – the most common cause of chronic peripheral neuropathy.

B12 or folate vitamin deficiencies can cause nerve damage and peripheral neuropathy.

Guillain-Barré syndrome is the name given to a specific type of peripheral neuropathy triggered by infection.

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an inflammation of nerve roots and peripheral nerves due to damage of fatty protective covering (myelin sheath) over the nerves.

Drugs – such as some chemotherapy medication and medicines used to treat HIV can cause damage to peripheral nerves. More than 40-50 drugs are known to cause neuropathy.

Poisons (toxins) – insecticides and solvents can cause peripheral nerve damage.
Cancers – peripheral neuropathy can occur in people with cancer ( lymphoma and multiple myeloma etc)

Alcohol excess – high alcohol levels in the body cause nerve damage.

Chronic kidney disease – Kidney disease and kidney failure can cause peripheral neuropathy.

Chronic liver disease.

Injuries – broken bones and tight plaster casts can put pressure directly on the nerves.

Infections – damage can be caused to peripheral nerves by some infections including shingles, HIV infection and Lyme disease.

Connective tissue diseases – rheumatoid arthritis, Sjögren’s syndrome and systemic lupus erythematosus.

Certain inflammatory conditions – conditions including sarcoidosis and coeliac disease can also cause peripheral neuropathy.

Hereditary diseases – Charcot-Marie-Tooth syndrome and Friedreich’s ataxia.