CIDP (Chronic inflammatory demyelinating polyneuropathy) is a neurological condition that involves inflammation in the nerves. The inflammation slowly but progressively destroys the protective covering of the nerves which is known as the myelin sheath. Symptoms can include slow but progressive weakness, pain and an impaired sensory function in the arms and legs. CIDP is therefore an inflammatory autoimmune disease, meaning that a person’s immune system begins to attack its peripheral nerves. CIDP is related to GBS (Guillain-Barre syndrome).
GBS (Guillain-Barré Syndrome)
GBS (Guillain-Barré Syndrome) is a peripheral neurological disorder affected by an inflammation of the peripheral nerves and is closely related to CIDP type neuropahty. Patients with GBS suffer from an a fast onset of symptoms including weakness, numbness and even paralysis of peripheries, including hands, feet, arms and legs. In bad cases, breathing and speech muscles can be impaired thus leading to a neurological crisis. GBS differs from CIDP in that GBS’s onset comes rapidly, usually manifesting itself within 24-hours whereas CIDP can take much longer, sometimes more than two months to onset. CIDP is chronic whereas the former is usually not.
- GBS (Guillain-Barré Syndrome)
- General Biological Terms
LPS (lipopolysaccharide) is a substance that exists on the outer membranes of some forms of bad bacteria. LPS protects bad bacteria in the digestive system (the gut) from being digested and thus destroyed. Although beneficial to bad bacteria, LPS is known as an endotoxin which is a toxic substance that is made by the bacteria itself. When LPS makes itself into the bloodstream of animals as shown in lab tests, it brings about severe inflammation in the body. LPS may be linked to autoimmune diseases like Rheumatoid arthritis and MS (Multiple Sclerosis).
Chronic inflammation refers to long-term inflammation, which can last for many months, years or even a lifetime. It often results from the body's failure to eliminate the cause of the inflammation, or an autoimmune disease whereby the body attacks healthy tissues mistaking it for a harmful entity or some form of long term irritant.
Inflammation is the body's attempt at healing itself whereby it tries to remove harmful diseases and disruptions in the body which include damaged cells and pathogens. Inflammation is a healing mechanism in the body, however, chronic inflammation can be detrimental as it may cause several disorders and diseases, including some kinds of cancer, RA (rheumatoid arthritis), ulcerative colitis, MS (multiple sclerosis), CIDP (Chronic inflammatory demyelinating polyneuropathy) and more.
- LPS (lipopolysaccharide)
Alzheimer’s is the most common manifestation of dementia which is a general terms for the loss of memory and cognitive abilities that are debilitating enough to negatively affect the proper functioning of life. Around 2/3rds of dementia cases are Alzheimer’s. Alzheimer’s starts slowly but worsens of the time. Its most common symptoms are difficulty in remembering recent events. As the disease progresses, its symptoms include problems in speech, mood problems, disorientation and behavioral problems. Alzheimer’s eventually leads to the loss of many bodily functions and ultimately death.
Peripheral neuropathy is a disorder of the peripheral nerves which is often characterized by numbness, limb weakness and pain. Certain types of neuropathy, such as CIDP type of neuropathy can be cured.
The peripheral nerves are the nerves that are outside the brain and the spinal cord.
Myelin is a fatty substance that envelops the axon (core of a nerve fiber) that speeds the transmission of nerve signals. The myelin is critical for the appropriate function of the nervous system.